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ID 25587
本文ファイル
著者
Yanagita, Kouichi
Shiraishi, Jun-ichi
Fujita, Masanori
キーワード
β-Endorphin
N-terminal fragment
feeding behavior
central nervous system
chick
NDC
動物学
抄録(英)
It is known that N-terminal fragments of β-endorphin have biological activities, such as an antagonism effect of β-endorphin (1–31) on the secretion of hormones or thermoregulation in mammals. We studied the effects of the N-terminal fragments on feeding behavior in male broiler chicks. Intracerebroventricular administration of β-endorphin (1–27) (0.4 nmol) stimulated feeding behavior compared with saline control during the 60-min experimental period. β-Endorphin (1–17) (2.0 nmol) also increased food intake at 30 min postinjection. Co-injection of either β-endorphin (1–27) or (1–17) was effective in reducing full-length β-endorphin-induced feeding in chicks. These data suggest that the N-terminal fragments of β-endorphin act as a partial agonist, and may regulate the activity of the central opioidergic system in chicks.
掲載誌名
Neuroscience Letters
442巻
2号
開始ページ
140
終了ページ
142
出版年月日
2008-09
出版者
Elsevier Ireland Ltd
ISSN
0304-3940
NCID
出版者DOI
PubMedID
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
author
権利情報
Copyright (c) 2008 Elsevier Ireland Ltd
関連情報URL(IsVersionOf)
http://dx.doi.org/10.1016/j.neulet.2008.07.018
部局名
生物圏科学研究科