Maintaining sanitation is important for well-being and dignity of people, and its consideration in water supply system is very important because majority of human diseases are water borne. These diseases might have enormous loss on economic and social sectors. Bangladesh being a highly populated country with inefficient waste management system, sanitation in drinking water supply has been a serious issue. This study reviewed existing literatures about the sanitation concerns in Bangladesh focusing on water supply system. The study shows that sanitation issue is poorly addressed in projects/programs related to water supply system. Some efforts have been made to integrate sanitation issue in water supply, but it has been poorly budgeted and activities of government and non-government activities are not integrated. To address this issue, this study recommend total sanitation framework. This framework could be useful to integrate sanitation issue in the current water supply system, bringing the innovations from government and non-government agencies in the same platform.