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ID 49997
本文ファイル
著者
SUEDA, Taijiro
MAEDA, Yoshiyuki
HAMANAKA, Yoshiharu
ISHIHARA, Hiroshi
MATSUURA, Yuichiro
KAJIHARA, Hiroki
キーワード
Myocardial protection
Cardiac transplantation
Bretschneider's solution
Heterotopic cardiac transplantation
NDC
医学
抄録(英)
Myocardial preservation by Bretschneider's solution (BR solution, Group I) with an intracellular like electrolyte and histidine buffer action was compared with EC-Bi solution (Group II) which has an extracellular like electrolyte and bicarbonate buffer action in the mongrel dogs. The PH and PCO2 of the effluent from the coronary sinus were maintained during myocardial ischemia for 3 hr but the lactate rose gradually in group I. The oxygen and lactate up-take ratio of the myocardium after re-perfusion was satisfactory and LV max dp/dt was also maintained at a high level in group I. Morphologically, myelin figure and mitochondrial deformation were more found in group II on electron microscopy.
A donor heart preserved for 3 hr in cold BR solution was transplanted in the left thoracic cavity in four mongrel dogs by the technique of the heterotopic cardiac transplantation. Resuscitation of cardiac pulsation was smooth and maintenance of the systemic circulation after transplantation was possible in every case. From these findings, it might be concluded that myocardial preservation using cold BR solution was useful for cardiac transplantation.
掲載誌名
Hiroshima Journal of Medical Sciences
36巻
3号
開始ページ
309
終了ページ
313
出版年月日
1987-09
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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