Incorporation of large guest molecules into liposomes via chemical reactions in lipid membranes

Organic and Biomolecular Chemistry 15 巻 8 号 1786-1791 頁 2017-02-28 発行
アクセス数 : 687
ダウンロード数 : 153

今月のアクセス数 : 2
今月のダウンロード数 : 0
ファイル情報(添付)
OBC_15-8_1786.pdf 1.86 MB 種類 : 全文
タイトル ( eng )
Incorporation of large guest molecules into liposomes via chemical reactions in lipid membranes
作成者
Tsuchiya Yuki
収録物名
Organic and Biomolecular Chemistry
15
8
開始ページ 1786
終了ページ 1791
抄録
The incorporation of hydrophobic guest molecules into lipid membranes by the exchange of the guest molecule from a cyclodextrin (CDx) complex to a liposome is limited to guest molecules that can be included in CDxs. To solve this problem, large guest molecules were incorporated into liposomes by chemical reactions of guest molecules in lipid membranes. Stable lipid-membrane-incorporated fullerene derivatives with large substituent(s) were prepared by Diels–Alder reactions in lipid membranes.
内容記述
Electronic supplementary information (ESI) available: Schematic representation of the premixing and exchange methods, 1H NMR spectra and UV-vis absorption spectra. See DOI: 10.1039/c6ob02343f
This work was supported by the Japanese Society for the Promotion of Science (JSPS) KAKENHI Grant-in-Aid for Scientific Research (B) (Grant No. JP16H04133) and a Grant-in-Aid for Challenging Exploratory Research (Grant No. JP16K13982).
NDC分類
化学 [ 430 ]
言語
英語
資源タイプ 学術雑誌論文
出版者
Royal Society of Chemistry
発行日 2017-02-28
権利情報
Copyright (c) 2017 The Royal Society of Chemistry
This is an open access article distributed under the terms of the Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0)
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 1477-0520
[DOI] 10.1039/c6ob02343f
[PMID] 27918054