このエントリーをはてなブックマークに追加
ID 46556
file
creator
Kainuma, Mika
Yamada, Ai
Katakawa, Kazuaki
NDC
Medical sciences
abstract
Enzymatic kinetic resolution of racemic esters of 2,2-disubstituted 5-hydroxychromenes was examined. Transesterification of acetate using Amano Lipase PS in the presence of t-BuOH was most effective to give the corresponding optically active acetate in 18% yield and 95% ee. The absolute configuration of the acetate was determined as R based on the conversion to teretifolione B with natural absolute configuration.
journal title
Heterocycles
volume
Volume 97
issue
Issue 1
start page
604
end page
611
date of issued
2018-05-18
publisher
The Japan Institute of Heterocyclic Chemistry
issn
0385-5414
1881-0942
publisher doi
language
eng
nii type
Journal Article
HU type
Journal Articles
DCMI type
text
format
application/pdf
text version
publisher
rights
Copyright (c) 2018 The Japan Institute of Heterocyclic Chemistry
department
Graduate School of Biomedical & Health Sciences