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ID 15024
file
creator
Hegazy, Mohamed-Elamir F.
Kuwata, Chika
Ahmed, Ahmed A.
subject
Biotransformation
Marchantia polymorpha
Hydrogenation
Hydroxylation
α-Santonin
Lancerodiol p-hydroxybenzoate
8,9-Dehydronootkatone
Nootkatone
NDC
Chemistry
abstract
The biotransformation of sesquiterpenoids having an α,β-unsaturated carbonyl group, such as -santonin (1), lancerodiol p-hydroxybenzoate (2), 8,9-dehydronootkatone (3) and nootkatone (4), with cultured suspension cells of Marchantia polymorpha was investigated. It was found that the C-C double bond of 1 and 2 was hydrogenated to give 1,2-dihydro--santonin (5) and 3,4-dihydrolancerodiol p-hydroxybenzoate (6), respectively, while the allylic position of the C-C double bond of 3 and 4 was hydroxylated to give 13-hydroxy-8,9-dehydronootkatone (7) and 9-hydroxynootkatone (8), respectively.
journal title
Journal of Molecular Catalysis B: Enzymatic
volume
Volume 39
issue
Issue 1-4
start page
13
end page
17
date of issued
2006-05
publisher
Elsevier B.V.
issn
1381-1177
ncid
publisher doi
language
eng
nii type
Journal Article
HU type
Journal Articles
DCMI type
text
format
application/pdf
text version
author
rights
Copyright (c) 2006 Elsevier B.V.
relation is version of URL
http://dx.doi.org/10.1016/j.molcatb.2006.01.032
department
Graduate School of Science