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ID 903
file
title alternative
Cytology in Hairy Cell Leukemia (HCL)
creator
Izumi, Takaki
Komura, Takashi
Kushima, Kimio
Yamashita, Misako
Tanaka, Kimio
subject
Hairy cell leukemia
B-cell
chromosome aberrations
NDC
Medical sciences
abstract
Hairy cell leukemia (HCL) is a chronic lympho-proliferative disease. The disease is clinically characterized by anemia, granulocytopenia, thrombocytopenia, monocytopenia, splenomegaly. This leukemia cells have peculiar shape with hairlike projection, and express mature B-cell antigens such as, CD19,CD20 and Ig heavy chain on their surface. Nuclear and cytoplasm area ratio was low. Cell biological observation and chromosome analysis were performed in 12 patients. Translocation at 14q32 was found in 2 patients and loss of chromosome 6 was found in one patient. These cytogenetical results suggest taht HCL is different disease from chronic lymphocytic leukemia.
journal title
Memoirs of the Faculty of Integrated Arts and Sciences, Hiroshima University. IV, Science reports
volume
Volume 26
start page
63
end page
70
date of issued
2000-12-28
publisher
広島大学総合科学部
contributor
国立情報学研究所
date of created
2006-03-21
issn
1340-8364
ncid
SelfDOI
language
jpn
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Integrated Arts and Sciences
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