Changes in Cardiovascular Risk Factors over a 24-Year Follow-Up Period : A Japanese Pediatric Cohort Study
Use this link to cite this item : https://ir.lib.hiroshima-u.ac.jp/00035017
ID | 35017 |
file | |
creator |
Kuwabara, Masahiko
Hirata, Hiroko
Sugino, Hirotoshi
Asaoka, Katsushi
Kondo, Haruyasu
Fujii, Kazuo
Matsubara, Hideki
Nakagawa, Takashi
Horie, Masanori
Ito, Hitoshi
Matsumoto, Haruyuki
Okamoto, Takuhiro
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subject | Asa Cohort Study
Cardiovascular risk factor
Follow-up study
BMI
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NDC |
Medical sciences
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abstract | This study examined changes in body mass index (BMI), fasting blood sugar (FBS), total cholesterol (TC) and HDL-cholesterol (HDL-C) levels over a 24-year follow-up period in a pediatric cohort. An appropriate starting age for intervention to prevent cardiovascular diseases is still unclear. The subjects were 655 children, aged 10-12. A follow-up survey was conducted when the subjects reached ages 13-15, 16-18, and 35-45, respectively, and height, weight, and blood tests including FBS, TC and HDL-C were examined. Forty (6%) of these subjects participated. BMI at ages 35-45 were significantly higher than those at ages 10-12 (p < 0.0001), 13-15 (p < 0.001), and 16-18 (p < 0.001). TC levels at ages 35-45 were significantly higher than at ages 10-12 (p < 0.0001), 13-15 (p < 0.0001), and 16-18 (p < 0.0001). BMI at the end of the follow-up (ages 35-45) had a significant correlation with BMI at ages 13-15 (R = 0.38, p = 0.041) and 16-18 (R = 0.41, p = 0.049). TC and HDL-C values at the end of the follow-up had a significant correlation with those at ages 10-12 (R = 0.55, p = 0.0004; R = 0.55, p = 0.016), 13-15 (R = 0.35, p = 0.045; R = 0.42, p = 0.015), and 16-18 (R = 0.47, p = 0.019; R = 0.44, p = 0.028). These results may suggest that intervention for children in Japan with cardiovascular risk factors should be initiated in the early years of life.
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journal title |
Hiroshima Journal of Medical Sciences
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volume | Volume 61
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issue | Issue 4
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start page | 85
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end page | 89
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date of issued | 2012-12
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publisher | Hiroshima University Medical Press
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issn | 0018-2052
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ncid | |
language |
eng
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nii type |
Departmental Bulletin Paper
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HU type |
Departmental Bulletin Papers
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DCMI type | text
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format | application/pdf
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text version | publisher
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rights | (c) Hiroshima University Medical Press.
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department |
Graduate School of Biomedical & Health Sciences
Health Service Center
Information Media Center
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他の一覧 |