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ID 38363
file
title alternative
パラコート中毒死の1例と生体試料中パラコートの迅速分析法
creator
Yamauchi, Junko
Yashiki, Mikiko
Une, Itsuko
Kojima, Tohru
Ito, Hisao
Kawachi, Shoji
Ohtani, Minako
subject
Paraquat
Poisoning
Distribution
Analysis
NDC
Medical sciences
abstract
In a case of fatal paraquat poisoning, the distribution of paraquat was determined by a) the column chromatographic method developed by Tompsett, b) the ion-pairing method, c) the deproteinization method both developed by Jarvie et al, and d) the precipitation method developed by the authors. The precipitation method relies on the use of a precipitate of paraquat with Reinecke's salt to extract paraquat from biological material, and the dithionite color reaction to detect paraquat. The paraquat concentrations obtained by the precipitation method approximated to those obtained by the column chromatographic method. The results indicate that the use of the precipitation method followed by the dithionite color reaction is suitable not only for forensic practice but also emergency analysis.

Since paraquat was not detected in the gastric contents collected at autopsy, and paraquat concentrations in the organs were much higher than the concentration in the heart blood, it seems that the hemodialysis and hemoperfusion were begun too late.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 32
issue
Issue 1
start page
93
end page
98
date of issued
1983-03
publisher
Hiroshima University School of Medicine
issn
0018-2052
ncid
pubmed id
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
University Medical Hospital
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