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ID 49947
file
creator
SAITOH, Hitoshi
MUNEOKA, Yojiro
subject
Crustacean peptide
Inhibitory action
Mytilus muscle
NDC
Medical sciences
abstract
It has been suggested that a peptide which belongs to the family of the arthropod neuropeptides, red pigment concentrating hormone (RPCH) and adipokinetic hormone (AKH), is also present in mollusc. In the present study, the effects of RPCH and AKH on the anterior byssus retractor muscle (ABRM), the pedal retractor muscle (PRM) and the heart of a bivalve, Mytilus edulis, were examined.
In most of the ABRMs examined, RPCH inhibited contractile response or catch-relaxing response or both, which were evoked by repetitive electrical pulses of stimulation. The threshold concentrations for the inhibition of contraction and relaxation were about 10^-7 M and 10^-8 M, respectively. In some of the muscles, however, both of the inhibitory effects or one of them was not found at 10^-6 M or less.
In most of the PRMs examined, RPCH also inhibited contractile response to repetitive electrical stimulation at 3 x 10^-8 M or higher, but in some of the muscles, it did not show the inhibitory effect at 3 x 10^-7 M.
Rhythmic activity in some hearts was inhibited by 10^-7 M or higher RPCH, but in the other hearts, the activity was not affected at 3 x 10^-6 M or was enhanced at 10^-6 M or higher.
AKH was found to be ineffective at 10^-6 M in all of the muscles of three kinds.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 35
issue
Issue 4
start page
389
end page
395
date of issued
1986-12
publisher
Hiroshima University School of Medicine
issn
0018-2052
ncid
pubmed id
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
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