In Vitro Thermochemotherapy of Human Osteosarcoma Cells with Cis-Dichlorodiammineplatinum (II)
Use this link to cite this item : https://ir.lib.hiroshima-u.ac.jp/00049920
| ID | 49920 |
| file | |
| creator |
YAMANE, Takashi
NAKABAYASHI, Hidekazu
ITO, Shiro
SUMII, Hiroshi
KAWAI, Akira
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| subject | Tissue culture
Thermochemotherapy
Human osteosarcoma cell
Cis-dichlorodiammineplatinum (II)
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| NDC |
Medical sciences
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| abstract | Human osteosarcoma cells (HuO-3Nl cells) and fibroblastic cells with normal human karyotype (HuO-3 cells) were derived from a patient with osteosarcoma. HuO-3N1 cells were more sensitive to heat treatment than HuO-3 cells. The combination of heat and cis-dichlorodiammineplatinum (II) (CDDP) exerted synergistic cytotoxity on HuO-3N1 cells, and was much less cytotoxic to HuO-3 cells than to HuO-3Nl cells. Therefore, thermochemotherapy with CDDP may be useful for treatment of human osteosarcoma.
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| journal title |
Hiroshima Journal of Medical Sciences
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| volume | Volume 35
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| issue | Issue 3
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| start page | 191
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| end page | 195
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| date of issued | 1986-09
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| publisher | Hiroshima University School of Medicine
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| issn | 0018-2052
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| ncid | |
| pubmed id | |
| language |
eng
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| nii type |
Departmental Bulletin Paper
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| HU type |
Departmental Bulletin Papers
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| DCMI type | text
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| format | application/pdf
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| text version | publisher
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| department |
Graduate School of Biomedical Science
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| 他の一覧 |
