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ID 35412
file
creator
Toyota, Naoyuki
Hieda, Masashi
Akiyama, Naoko
Terada, Hiroaki
Matsuura, Noriaki
Nishiki, Masayo
Kono, Hirotaka
Kohno, Hiroshi
Irei, Toshimitsu
Yoshikawa, Yukinobu
Kuraoka, Kazuya
Taniyama, Kiyomi
subject
Gadoxetate disodium (EOB)
Hepatocellular carcinoma (HCC)
Multi-detector row CT (MDCT)
NDC
Medical sciences
abstract
The purpose of this study was to evaluate the diagnostic capability of gadoxetate disodium (Gd-EOB)-MRI for the detection of hepatocellular carcinoma (HCC) compared with multidetector CT (MDCT). Fifty patients with 57 surgically proven HCCs who underwent Gd-EOB-MRI and MDCT from March 2008 to June 2011 were evaluated. Two observers evaluated MR and CT on a lesionby-lesion basis. We analyzed sensitivity by grading on a 5-point scale, the degree of arterial enhancement and the differences in histological grades in the diffusion-weighted images (DWI). The results showed that the sensitivity of Gd-EOB-MRI was higher than that of MDCT especially for HCCs that were 1 cm in diameter or smaller. The hepatobiliary phase was useful for the detecting of small HCC. We had few cases in which it was difficult to judge HCC in the arterial enhancement between MRI and MDCT. In the diffusion-weighted image, well differentiated HCC tended to show a low signal intensity, and poorly differentiated HCC tended to show a high signal intensity. In moderately differentiated HCC's, the mean diameter of the high signal intensity group was larger than that of the low signal intensity group (24.5 mm vs. 15.8 mm). In conclusion, Gd-EOB-MRI tended to show higher sensitivity compared to MDCT in the detection of HCC.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 62
issue
Issue 3
start page
55
end page
61
date of issued
2013-09
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
rights
(c) Hiroshima University Medical Press.
department
Graduate School of Biomedical & Health Sciences
University Medical Hospital
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