Malignant Paraganglioma Arising from the Posterior Mediastinum : A Case Report and Review of the Literature
Use this link to cite this item : https://ir.lib.hiroshima-u.ac.jp/00037742
ID | 37742 |
file | |
creator |
Isobe, Takeshi
Oguri, Tetsuya
Daga, Haruko
Ishikawa, Hisanobu
Ochiai, Mari
Kitaguchi, Souichi
Ishioka, Shinichi
Yamakido, Michio
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subject | Malignant paraganglioma
Posterior mediastinum
p53
ras
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NDC |
Medical sciences
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abstract | An unusual case of paraganglioma of posterior mediastinum occurred in a young adult with local recurrence and multiple distant metastasis. Because of its rarity, the determinants of prognosis factor between benign and malignant paraganglioma are uncertain. In this case, we investigated abnormalities of the p53 gene and ras gene mutations in tissues of primary and metastatic lesions. Neither abnormalities of p53 gene nor ras gene mutations were detected. The molecular approach is recommended as a means of clarifying the trend towards the malignancy of paraganglioma.
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journal title |
Hiroshima Journal of Medical Sciences
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volume | Volume 48
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issue | Issue 4
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start page | 123
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end page | 127
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date of issued | 1999-12
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publisher | Hiroshima University Medical Press
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issn | 0018-2052
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ncid | |
language |
eng
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nii type |
Departmental Bulletin Paper
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HU type |
Departmental Bulletin Papers
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DCMI type | text
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format | application/pdf
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text version | publisher
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department |
Graduate School of Biomedical Science
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他の一覧 |