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ID 37725
file
creator
Kanahara, Koji
Yorioka, Noriaki
Ogata, Satoshi
Ohira, Norihisa
Oobayashi, Makoto
Kiso, Tetsuji
Harada, Yoshiko
Komiya, Hiroshi
Asakimori, Yukiteru
Taniguchi, Yoshihiko
Yamakido, Michio
subject
Aortitis syndrome (Takayasu arteritis)
Immunoglobulin A nephropathy
Human leukocyte antigen
NDC
Medical sciences
abstract
A 51-year-old woman, who had both aortitis syndrome (Takayasu arteritis) and IgA nephropathy, presented with hypertension, fever, a high erythrocyte sedimentation rate, high C-reactive protein and serum IgG levels, proteinuria, and renal dysfunction. Renal arteriography showed stenosis and poststenotic dilatation at the origin of the right renal artery, as well as tortuosity of the left renal artery branches and marked atrophy of the left kidney. Renal biopsy showed IgA nephropathy with deposits of IgA, C3, and fibrinogen in the glomeruli and arteriolosclerosis. The present patient had human leukocyte antigen (HLA)-B 52, which is reported to be related to the aortitis syndrome, as well as HLA-DR 4, which is possibly related to IgA nephropathy, suggesting that HLA status may be involved in the pathogenesis of both diseases.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 48
issue
Issue 1
start page
25
end page
29
date of issued
1999-03
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
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