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ID 38009
file
creator
Hong, He-Qun
Asahara, Toshimasa
Ito, Hisao
Watanabe, Hiroshi
Kimura, Atsuo
Urushihara, Takashi
Marubayashi, Seiji
Fukuda, Yasuhiko
Nishiki, Masayuki
Dohi, Kiyohiko
subject
Rat liver
Portal arterialization
Heterotopic auxiliary transplantation
NDC
Medical sciences
abstract
The effect of portal arterialization was examined in 20 heterotopic auxiliary rat livers. Portal blood was supplied from recipient iliac artery (0.58 mm in diameter) connected to the donor portal vein using the cuff technique. Portal hypertension caused by arterial blood pressure resulted in the immediate operative death by bleeding in four of the rats (20%) from the spontaneous rupture of the graft capsule. Severe graft congestion was noticed at autopsy 3-14 days after transplantation in 13 rats. Massive portal and sinusoidal congestion and focal hemorrhagic necrosis were confirmed by pathological examination. The results of our study demonstrate that the portal arterialization used in the auxiliary rat liver transplantation would not be applicable unless the optimal hemodynamic condition is warranted.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 40
issue
Issue 1
start page
29
end page
33
date of issued
1991-03
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
pubmed id
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
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