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ID 38143
file
creator
Nakamura, Fukashi
Sasaki, Hiroshi
Ueda, Masanori
Yamanoue, Michio
Kajihara, Hiroki
subject
Fulminant hepatitis
Hepatitis virus type B
HBs antigen
HBs antibody
IgM HBc
NDC
Medical sciences
abstract
A case of fulminant viral hepatitis type B in the late stage of pregnancy was successfully treated with glucagon-insulin therapy, corticosteroids and other drugs. A 26-year-old female (housewife and primipara) suddenly developed severe hepatic dysfunction and disturbance of consciousness at the 36th week of pregnancy. Sequential blood examinations revealed early response to HBs antibody and delayed response to HBc antibody but HBs antigen was not detectable. The two antibodies disappeared from the serum rapidly and anti-HBc IgM remained undetectable throughout the clinical course of the acute hepatitis. It is not rare for HBs antibody to appear and for HBs antigen to disappear rapidly in the early stage of the clinical course of fulminant viral hepatitis type B. Anti-HBc IgM is considered valuable in the diagnosis of viral hepatitis type B. However, the present case demonstrated that anti-HBc IgM may be undetectable throughout the clinical course in some cases of viral hepatitis type B.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 37
issue
Issue 1
start page
45
end page
49
date of issued
1988-03
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
pubmed id
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
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