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ID 38137
file
creator
Sakano, Takashi
Hamasaki, Takashi
Shimizu, Hiroshi
Harada, Yoshiaki
Ueda, Kazuhiro
subject
Intravenous immunoglobulin
Myasthenia gravis
NDC
Medical sciences
abstract
A 7-year-old girl with ocular myasthenia gravis (MG) refractory to prednisolone and anticholinesterase compounds was treated with high-dose intravenous immunoglobulin (IVIg). Ocular symptoms disappeared rapidly by the administration of IVIg 300 mg/kg/day for five consecutive days. Booster infusions of IVIg at an interval of 2 weeks appeared to be effective in maintaining a remission at least as an adjunct to prednisolone. The levels of acetylcholine receptor (AchR) antibodies were not correlated with clinical improvement or aggravation. Thus, high-dose IVIg may be useful in refractory cases of MG, allowing a reduction in doses of immunosuppressive drugs.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 37
issue
Issue 1
start page
7
end page
9
date of issued
1988-03
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
pubmed id
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
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