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ID 20325
file
creator
Nishimura, Haruki
Hamada, Taizo
Makihira, Seicho
Samaranayake, Lakshman P.
subject
biofilm
Candida albicans
Candida tropicalis
saliva
serum
thigmotropism
abstract
The biofilm formation of the oral fungal pathogen Candida on denture acrylic strips coated with saliva or serum was examined in relation to the ability to induce hyphae by thigmotropic reaction, using C. albicans (4 isolates), C. glabrata (3 isolates) and C. tropicalis (3 isolates). Both the degree of biofilm formation and the amount of hyphae exhibiting thigmotropism varied depending upon both the species and strains of Candida. Although there was no significant correlation between the amount of hyphae induced by thigmotropic reaction of fungal isolates and biofilm formation on uncoated control specimens (r = 0.577; p < 0.05), the ability of hyphae induced by thigmotropic reaction significantly correlated with the amount of both saliva- and serum-admixed biofilms (r = 0.734; p < 0.05 and r = 0.793; p < 0.01, respectively). Taken together our in vitro data suggested that the hyphal induction by thigmotropic reaction is of importance in candidal biofilm formation on saliva- or serum-coated acrylic surfaces.
journal title
Mycopathologia
volume
Volume 144
issue
Issue 3
start page
125
end page
129
date of issued
1998-12
publisher
Springer
issn
0301-486X
ncid
publisher doi
pubmed id
language
eng
nii type
Journal Article
HU type
Journal Articles
DCMI type
text
format
application/pdf
text version
author
rights
Copyright (c) 1998 Springer-Verlag. "The original publication is available at www.springerlink.com"
relation url
department
Graduate School of Biomedical Science