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ID 20319
file
creator
Jin, Chen
Hamada, Taizo
Murata, Hiroshi
abstract
In the present study, the growth of a single isolate of Candida albicans on seven saliva-, serum-coated or protein free (uncoated), thermocycled (4–70 °C for 1 min, respectively; 0, 1000 and 10 000 times) commercial resilient lining materials was investigated by monitoring pH changes in growth media. The inhibitory effect of the tissue conditioners on fungal growth was observed using three parameters, i.e. (i) the delay in the onset of the rapid decline in pH, (ii) the reduction in the rate of pH change and (iii) the pH minima reached. In the case of control soft liners (not thermocycled and uncoated), the antifungal effect appeared to depend upon the type of commercial soft liner used. Thus, an initial delay in pH decline and a very high pH minima were observed with fluoric and heat-cured silicone materials. High pH minima were also observed with cold-cured acrylic soft liners, whereas cold-cured silicone materials did not significantly differ from heat-cured acrylic resin (P>0·05). However, the antifungal effect of the materials was significantly reduced both by thermal cycling (anova, P<0·01) and a layer of protein coating (saliva, P<0·05; serum, P<0·01). These results, taken together, suggest that the ageing of the materials and the biological fluids of the host, particularly serum, promote yeast growth on soft lining materials.
journal title
Journal of Oral Rehabilitation
volume
Volume 27
issue
Issue 1
start page
41
end page
51
date of issued
2000-01
publisher
Blackwell Publishing
issn
0305-182X
ncid
publisher doi
pubmed id
language
eng
nii type
Journal Article
HU type
Journal Articles
DCMI type
text
format
application/pdf
text version
author
rights
Copyright (c) 2000 Blackwell Publishing. The definitive version is available at www.blackwell-synergy.com
relation url
department
Graduate School of Biomedical Science