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ID 17102
file
creator
Kohriyama, Tatsuo
Arimura, Kimiyoshi
subject
Invasive thymoma
Limbic encephalitis
Voltage-gated potassium channel antibody
NDC
Medical sciences
abstract
Recently, limbic encephalitis (LE) associated with Voltage-gated potassium channel antibody (VGKC-Ab) has been postulated as a new autoimmune disorder. Most previously reported cases of VGKC-Ab-associated LE were non-paraneoplastic, and reports of a paraneoplastic type are rare. Here we describe a 59-year-old woman with paraneoplastic VGKC-Ab-associated LE preceding the recurrence of invasive thymoma. There was a close temporal relationship between the clinical course and the changes of the VGKC-Ab titer. Unlike many of the non-paraneoplastic VGKC-Ab-associated LE cases, our cases showed the more extensive high intensity lesions on MRI and the absence of seizure and hyponatremia.
journal title
Journal of the Neurological Sciences
volume
Volume 250
issue
Issue 1-2
start page
167
end page
169
date of issued
2006-12-01
publisher
Elsevier
issn
0022-510X
ncid
publisher doi
pubmed id
language
eng
nii type
Journal Article
HU type
Journal Articles
DCMI type
text
format
application/pdf
text version
author
rights
Copyright (c) 2006 Elsevier Ltd.
relation is version of URL
http://dx.doi.org/10.1016/j.jns.2006.08.003
department
Graduate School of Biomedical Science