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ID 37800
file
creator
Yorioka, Noriaki
Taniguchi, Yoshihiko
Ito, Takafumi
Katsutani, Masahira
Amimoto, Dai
Nishida, Yoji
Kushihata, Shigeyuki
Oda, Hiroaki
Yamakido, Michio
subject
Continuous ambulatory peritoneal dialysis
Dialysis-related peritonitis
Vancomycin
NDC
Medical sciences
abstract
Vancomycin therapy is frequently used for peritonitis in patients on peritoneal dialysis, but the emergence of resistance has been reported. We evaluated the efficacy of a single intraperitoneal dose of vancomycin for peritonitis in peritoneal dialysis patients. We assessed 24 episodes of peritonitis in 16 patients, and compared clinical parameters between responders and nonresponders. Vancomycin was effective for 12 patients (18 out of 24 episodes, 75.0%). Nonresponders had a significantly higher initial C-reactive protein level and dialysis fluid leukocyte count, and the mean serum albumin over three months before onset was significantly lower than in responders. Patients with a serum albumin level 3.0 g/dl or more were significantly more likely to respond than those with a level less than 3.0 g/dl. In conclusion, it seems reasonable for peritonitis patients with a mild inflammatory response and a serum albumin 3.0 g/dl or more to receive intraperitoneal vancomycin on an outpatient basis.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 47
issue
Issue 3
start page
105
end page
107
date of issued
1998-09
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
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