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ID 37111
file
creator
Aoi, Satomi
Miyake, Takashi
Harada, Toshihide
Ishizaki, Fumiko
Ikeda, Hiromi
Nitta, Yumiko
Iida, Tadayuki
Chikamura, Chiho
Tamura, Noriko
Nitta, Kohsaku
subject
Neck circumference
Obesity
Metabolic abnormality
BaPWV
NDC
Medical sciences
abstract
Subcutaneous fat depots play an important role in regulating metabolic profile in Japanese postmenopausal women. We investigated the possibility of neck circumference (NC) as a surrogate marker for metabolic disease risk estimates in Japanese postmenopausal women. We examined the association of NC with several markers of insulin resistance, lipid metabolism and atherosclerosis in 64 healthy postmenopausal women aged 63.6 ± 7.1 years in community-based samples in Japan. As a result, NC was significantly associated with indices of whole body obesity and visceral fat accumulation, such as body mass index (BMI) and waist circumference (WC). In the analysis of biomarkers for insulin resistance, NC was positively correlated to HbA1c, homeostasis model assessment ratio (HOMA-R) and leptin. In addition, an increase in triglycerides (TG) and a decrease in HDL-cholesterol (HDL-C) were also associated with NC. Interestingly, NC was also associated with atherosclerosis-related indices. The measurement of NC is an easy, inexpensive and reproducible method for assessment of obesity, and a possible predictor to identify the risk for future metabolic diseases in Japanese postmenopausal women.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 63
issue
Issue 4
start page
27
end page
32
date of issued
2014-12
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
rights
Copyright (c) Hiroshima University Medical Press
department
Graduate School of Biomedical & Health Sciences
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