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ID 37694
file
creator
Hayashi, Ken
Shimamoto, Fumio
subject
Epithelial myoepithelial carcinoma
S-100 protein
Immunohistochemistry
NDC
Medical sciences
abstract
A 69-year-old japanese female with epithelial myoepithelial carcinoma (EMC) in the parotid gland is reported. The tumor, 3.5 ×4.0 × 1.5 cm in size, was located in the left parotid gland. Histopathological examination of the surgically removed tumor revealed that it was composed of double-layered, tubule-like structures formed by inner eosinophilic ductal cells and outer clear cells, as well as solid clear cell nests. The unique histological finding of this tumor was that it had a cribriform-like arrangement of myoepithelial cells resembling an adenoid cystic carcinoma. On the other hand, the typical ductal and myoepithelial components of EMC showed the usual biphasic pattern and the expected immunophenotypes, with expression of low molecular weight cytokeratins, CAM 5.2 and EMA in the ductal part, and smooth muscle actin, S-100 protein, and vimentin in the myoepithelial component.
description
Part of this case report was presented at the 40th Hiroshima Assembly of Pathologists (May 20, 2000).
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 50
issue
Issue 4
start page
101
end page
104
date of issued
2001-12
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
University Medical Hospital
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