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ID 38296
file
title alternative
末梢神経損傷における再生線維の方向性に関する実験的研究
creator
subject
Regenerating nerve fibers
Orientation
Chemotaxis
Contact guidance
NDC
Medical sciences
abstract
The objective of this study was to ascertain how the orientation of regenerating fibers of the proximal stump of severed peripheral nerves is determined at time of growth. In other words, a gap was intentionally created between the both stumps of severed peripheral nerves to determine whether regenerating fibers are guided in the direction of the distal stump or if they grow randomly. The following results were obtained.

1) Regenerating fibers sprouting from the proximal stump definitely extend in the direction of the distal stump.

2) Even when the distal stump is replaced with a nerve fragment, the regenerating fibers grow in that direction.

These results are completely different from those of Weiss and Taylor, and thus the conclusion was reached that the possibility the orientation of regenerating fibers is determined by chemotaxis cannot be ruled out.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 32
issue
Issue 4
start page
389
end page
406
date of issued
1983-12
publisher
Hiroshima University School of Medicine
issn
0018-2052
ncid
pubmed id
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
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