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ID 27689
file
creator
Maruishi, Masaharu
Muranaka, Hiroyuki
Kondo, Keita
subject
Diffuse axonal injury
errorless learning
errorful learning
fMRI
NDC
Medical sciences
abstract
Primary objective: Errorless learning has been reported to be effective in the rehabilitation of patients with impaired cognitive functions following brain injury. This study compared brain activations in errorless learning (EL) and errorful learning (EF) in patients with diffuse axonal injury (DAI) using a functional magnetic resonance imaging (fMRI). Methods and procedures: The participants were 13 patients with DAI. Thirteen healthy individuals were evaluated as a control group. The participants learned words under the EL and EF conditions in advance and performed the recognition task during fMRI scanning. Main outcomes and results: EL in the control group was significantly faster than EF (p = 0.005), but not in the DAI group. EL in the DAI group scored significantly higher than EF (p = 0.026). An fMRI showed significant activations in the posterior cingulate gyrus (BA 31) and precuneus (BA 7) in the control group when EF EL, but in the precuneus (BA 7, 31) and bilateral inferior parietal lobules (BA 39, 40) in the DAI group. Conclusions: These results indicate the disadvantage of EF and advantage of EL to DAI patients. The findings also reflect brain plasticity in patients with DAI in the chronic phase.
journal title
Brain Injury
volume
Volume 23
issue
Issue 4
start page
291
end page
298
date of issued
2009
publisher
Taylor & Francis Ltd
issn
0269-9052
ncid
publisher doi
language
eng
nii type
Journal Article
HU type
Journal Articles
DCMI type
text
format
application/pdf
text version
author
rights
Copyright (c) 2009 Taylor & Francis. This is an electronic version of an article published in "Brain Injury, Volume 23, Issue 4 April 2009, pages 291 - 298" Disability and Rehabilitation is available at: http://dx.doi.org/10.1080/02699050902794855
relation url
department
Graduate School of Biomedical Science