In order to know the correlation between amphetamine concentrations in saliva and whole blood, saliva and blood samples of 51 methamphetamine abusers were collected up to 11 days after the last intake of methamphetamine. Amphetamine concentrations in saliva were higher than those in whole blood in all but one 70 pair samples. Ratio of amphetamine concentrations in saliva to those in whole blood were highly varied depending on the pH of saliva, but ratio were correlated with the pH of saliva. These results suggest that saliva is better than blood for amphetamine analysis, and that amphetamine concentrations in whole blood and the intoxication level of a methamphetamine abuser can be estimated by the amphetamine concentration and the pH of saliva.