The Institute of Agriculture and Animal Science (IAAS), Tribhuvan University has introduced Applied Ethnobotany as one of the courses of postgraduate program in Conservation Ecology since 2004. This paper will highlight the course curriculum development process of Tribhuvan University and course enrollment by the IAAS students. Then, it will discuss on learning approaches and methods followed for this subject. In addition, this paper will attempt to summarize the selected ethnobotanical researches conducted by the faculties and students of the IAAS alone or in partnership with ethnic communities and non-governmental organizations (NGOs); and try to highlight the necessity of developing partnerships and networking with academic and research organizations for promoting ethnobotany education and research of the IAAS for producing high quality human resources in this field. Finally, this paper will highlight some directions to enhance capacity of the teachers and institution for quality and effective teaching and learning processes.