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ID 49996
file
creator
NAOMOTO, Yoshio
TANAKA, Noriaki
KONDO, Hidenori
MOTODA, Ryuichi
ANDO, Shunsaku
KURIMOTO, Masasi
ORITA, Kunzo
subject
Nude mouse
Hamster
Human tumor
Xenograft
NDC
Medical sciences
abstract
We comparatively examined nude mice and hamsters as to their suitability as recipients of human cancers. CD-1 nude mice and golden hamsters immunosuppressed with anti-hamster thymocyte serum were used. Nude mice were superior in the areas of primary transplantation and subsequent transfer and maintenance. However, growth of tumors transplantable to both animals (a lung cancer line LC-1, a colon cancer line RPMI4788) tends to be better in hamsters than in nude mice. The better development of LC-1 and RPMI4 788 cells in hamsters than in nude mice appears to be related to the superior gain in body weight shown by hamsters.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 36
issue
Issue 3
start page
305
end page
308
date of issued
1987-09
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
pubmed id
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
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