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ID 49897
file
creator
KOMAI, Tadashi
HAMADA, Takeshi
HAMADA, Taizo
TAMAMOTO, Mitsuhiro
SHIGETO, Naofumi
subject
Oral candidiasis
Candida albicans
Denture stomatitis
NDC
Medical sciences
abstract
Denture stomatitis is often observed in the denture-bearing mucosa. Candida albicans and related species are now believed to play a major role as a pathogenic factor in denture stomatitis. If systemic predisposing factors are present, denture stomatitis will sometimes develop into acute pseudomembraneous candidiasis. In acute pseudomembraneous candidiasis, the patients cannot take foods, and dehydration often occurs. This vicious cycle is the most important cause of increase in the growth of Candida species. Therefore, in order to improve the patient's physical condition, infusion therapy will be the first choice of treatment. The purpose of this study was to investigate the clinical effect of infusion therapy in combination with local antimycotic drugs on this type of candidiasis.
We observed 4 cases of acute pseudomembraneous candidiasis induced by removable dentures and tried to treat these patients with infusion therapy (5% dextrose in lactatedRinger's solution) and local antimycotic drugs (Nystatin ointment or 1 % Miconazole nitrate cream). The acute inflammatory symptoms were significantly decreased by this therapy.
The result of this study indicated that infusion therapy in combination with local antimycotic drugs was clinicaly effective on acute pseudomembraneous candidiasis induced by Candida-induced denture stomatitis.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 35
issue
Issue 1
start page
45
end page
48
date of issued
1986-03
publisher
Hiroshima University School of Medicine
issn
0018-2052
ncid
pubmed id
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
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