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ID 49148
file
creator
Katakawa, Kazuaki
abstract
Pyranonaphthoquinone natural products are widely distributed in plants and microorganisms and have diverse biological activities. Angular benzochromenes are a small class of natural products isolated from Conospermum and Pentas plants. Of these, conocurvone was isolated from Conospermum as a trimeric pyranonaphthoquinone that has potent anti-HIV activity. We have focused on the total synthesis of compounds that exhibit biological activity or whose activity is enhanced upon oligomerization. This review describes the discovery and biological activities of the trimeric pyranonaphthoquinone conocurvone and related compounds, as well as our and other researchers’ synthetic studies toward monomeric pyranonaphthoquinones.
description
This work was partially supported by The Uehara Memorial Foundation, a Grant from Musashino Joshi-Gakuin, and JSPS KAKENHI Grant Number JP19K06975.
journal title
Heterocycles
volume
Volume 100
issue
Issue 2
start page
177
end page
193
date of issued
2019-12-23
publisher
The Japan Institute of Heterocyclic Chemistry
issn
1881-0942
publisher doi
language
eng
nii type
Journal Article
HU type
Journal Articles
DCMI type
text
format
application/pdf
text version
publisher
rights
Copyright (c) 2019 The Japan Institute of Heterocyclic Chemistry
This is the uncorrected proof, and is not the published version. Please cite only the published version. この論文は著者校正前原稿であり、出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。
relation url
department
Graduate School of Biomedical & Health Sciences



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