Formation of β‐(1,3‐1,6)‐D‐glucan‐complexed [70]fullerene and its photodynamic activity towards macrophages

Ikeda, Atsushi; Akiyama, Motofusa; Sugikawa, Kouta; Koumoto, Kazuya; Kagoshima, Yuta; Li, Jiawei; Suzuki, Toshio; Nagasaki, Takeshi

doi:10.1039/c6ob02747d

Use this link to cite this item : https://ir.lib.hiroshima-u.ac.jp/00046206

ID	46206
file	OBC_15-9_1990.pdf 853 KB
creator	Ikeda, Atsushi Profile Akiyama, Motofusa Sugikawa, Kouta Profile Koumoto, Kazuya Kagoshima, Yuta Li, Jiawei Suzuki, Toshio Nagasaki, Takeshi
NDC	Chemistry
abstract	[70]Fullerene was dissolved in water by the complexation with β‐1,3‐glucan using a mechanochemical high‐speed vibration milling apparatus. The photodynamic activity of β‐1,3 glucan‐complexed C70 was highly dependent on the expression level of dectin‐1 on the cell surfaces of macrophages. The photodynamic activity increased as a result of a synergistic effect between β‐1,3‐glucan‐complexed 1’‐acetoxychavicol acetate and the C70 complex.
description	This work was supported by JSPS KAKENHI Grant‐in‐Aid for Scientific Research (B) (Grant No. JP16H04133), Grant‐in‐Aid for Scientific Research (C) (Grant No. 26350528) and Grant‐in‐Aid for Challenging Exploratory Research (Grant No. JP16K13982).
journal title	Organic and Biomolecular Chemistry
volume	Volume 15
issue	Issue 9
start page	1990
end page	1997
date of issued	2017-03-01
publisher	Royal Society of Chemistry
issn	1477-0520
publisher doi	10.1039/c6ob02747d
pubmed id	28177008
language	eng
nii type	Journal Article
HU type	Journal Articles
DCMI type	text
format	application/pdf
text version	author
rights	Copyright (c) 2017 The Royal Society of Chemistry This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
department	Graduate School of Engineering

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