Epithelial-myoepithelial Carcinoma of the Parotid Gland with Adenoid Cystic Carcinoma-like Features : a case report with immunohistochemical study

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Title ( eng )
Epithelial-myoepithelial Carcinoma of the Parotid Gland with Adenoid Cystic Carcinoma-like Features : a case report with immunohistochemical study
Creator
Hayashi Ken
Shimamoto Fumio
Source Title
Hiroshima Journal of Medical Sciences
Volume 50
Issue 4
Start Page 101
End Page 104
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
A 69-year-old japanese female with epithelial myoepithelial carcinoma (EMC) in the parotid gland is reported. The tumor, 3.5 ×4.0 × 1.5 cm in size, was located in the left parotid gland. Histopathological examination of the surgically removed tumor revealed that it was composed of double-layered, tubule-like structures formed by inner eosinophilic ductal cells and outer clear cells, as well as solid clear cell nests. The unique histological finding of this tumor was that it had a cribriform-like arrangement of myoepithelial cells resembling an adenoid cystic carcinoma. On the other hand, the typical ductal and myoepithelial components of EMC showed the usual biphasic pattern and the expected immunophenotypes, with expression of low molecular weight cytokeratins, CAM 5.2 and EMA in the ductal part, and smooth muscle actin, S-100 protein, and vimentin in the myoepithelial component.
Keywords
Epithelial myoepithelial carcinoma
S-100 protein
Immunohistochemistry
Descriptions
Part of this case report was presented at the 40th Hiroshima Assembly of Pathologists (May 20, 2000).
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University Medical Press
Date of Issued 2001-12
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312