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ID 34944
本文ファイル
著者
Shibata, Yuuka
Ikeda, Hiroaki
キーワード
Topical corticosteroid
Physical property
Ointment
Cream
NDC
医学
抄録(英)
The purpose of this study is to elucidate the physical properties of various commercially available topical corticosteroid preparations. We compared comfort after application and the physical properties affecting topical application among brands of commercially available topical corticosteroid ointments and creams to identify factors affecting quality of life after application. We investigated 12 commercially available brands of topical corticosteroid preparations (6 creams and 6 ointments), all classified as "potent" corticosteroid in Japan. Subjects were 122 healthy volunteers at 11 hospitals, all of whom had given their informed consent for this study. Physical properties were compared among test preparations as well as standard preparations. Ranked high in comfort, Nerisona(R) cream was easy to spread, odorless, and low in viscosity. Overall, it displayed better qualities than other creams tested. The spreadability of Rinderon(R)-DP ointment and Antebate(R) ointment ranked higher than other preparations, suggesting that these ointments may reduce mechanical irritation to lesions during topical application. The results of this study could be used by dermatologists and pharmacists to aid preparation choice and improve compliance with application recommendations.
掲載誌名
Hiroshima Journal of Medical Sciences
56巻
3・4号
開始ページ
33
終了ページ
39
出版年月日
2007-12
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
(c) Hiroshima University Medical Press.
部局名
病院
医歯薬学総合研究科
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