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ID 38315
本文ファイル
別タイトル
人胎児期,新生児期,幼児期,成人期造血における巨核球面積の変動
著者
Izumi, Takaki
Kawakami, Masahito
Enzan, Hideaki
Ohkita, Takeshi
キーワード
Megakaryocyte size
Micromegakaryocyte
Fetal hematopoiesis
NDC
医学
抄録(英)
It has been reported that the appearance of small megakaryocytes can be detected in various blood diseases and in fetal hematopoiesis.

In the studies reported herein, we have investigated the age changes in the area of megakaryocytes during fetal stage to the newborn infant, infant, and adult stage.

The megakaryocyte increased in size from ago of 5 months to 10 months in fetal stage, and then at the age of one year after birth reached a size almost identical to that of adults.

In comparing the megakaryocyte area by fetal age, however, the significant difference was not observed in the hepatic and the bone marrow hematopoiesis at the age of 5 and 7 months.

The results in comparing the area ratio of the nucleus to the cytoplasm of megakaryocytes indicated that the nucleus of fetel megakaryocytes is generally smaller than that of adult marrow megakaryocytes.

This finding suggests that the size of the nucleus of megakaryocytes enlarges with increase in the area of megakaryocytes.

It is also considered that the functional or morphological changes of megakaryocytes may reflect the function or morphology of the platelet.
掲載誌名
Hiroshima Journal of Medical Sciences
32巻
3号
開始ページ
257
終了ページ
260
出版年月日
1983-09
出版者
Hiroshima University School of Medicine
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
原爆放射線医科学研究所
医歯薬学総合研究科
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