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ID 38057
本文ファイル
著者
Kuroi, Katsumasa
Sato, Yukio
Takayama, Takahiko
Baba, Nobutoshi
Yamaguchi, Yoshiyuki
Toge, Tetsuya
キーワード
Gastric cancer
Lymphocyte subpopulations
Peripheral blood
Spleen
Monoclonal antibodies
NDC
医学
抄録(英)
Lymphocyte subpopulations in peripheral blood and the spleen from gastric cancer patients were identified by either single or two color analysis with fluorescence activated cell sorter-IV (FACS-IV) using monoclonal antibodies. The absolute and percentages of CD3+ (mature T) cells and CD4 + (helper/inducer T) cells in peripheral blood from the advanced cancer patients were significantly lower than those from normal healthy controls. In peripheral blood, a significant decrease of CD4 + cells was due to the decrease of CD4 + CD45RA + (suppressor inducer T) cells, while CDS+ CD11b+ (suppressor T) cells tended to increase with progress of the disease. CD4+ CD45RA + cells located more predominantly in peripheral blood and spleen than in the splenic vein, while CDS+ CD11b+ cells were more predominant in the splenic vein.
掲載誌名
Hiroshima Journal of Medical Sciences
39巻
2号
開始ページ
23
終了ページ
27
出版年月日
1990-06
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
原爆放射線医科学研究所
医歯薬学総合研究科
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