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ID 47064
本文ファイル
Thumnail 393598.pdf 1.71 MB
著者
Shigemori, Suguru
Oshiro, Kazushi
Wang, Pengfei
Wang, Yeqin
Sato, Takashi
Uyeno, Yutaka
Shimosato, Takeshi
抄録(英)
Previous studies showed that hydrolysates of 𝛽-lactoglobulin (BLG) prepared using gastrointestinal proteases strongly inhibit dipeptidyl peptidase-IV (DPP-IV) activity in vitro. In this study, we developed a BLG-secreting Lactococcus lactis strain as a delivery vehicle and in situ expression system. Interestingly, trypsin-digested recombinant BLG from L. lactis inhibited DPP-IV activity, suggesting that BLG-secreting L. lactis may be useful in the treatment of type 2 diabetes mellitus.
内容記述
The study was supported by a grant from the Iijima Memorial Foundation for the Promotion of Food Science and Technology to Takeshi Shimosato.
掲載誌名
BioMed Research International
å·»
2014å·»
開始ページ
393598
出版年月日
2014-08-03
出版者
Hindawi Publishing Corporation
ISSN
2314-6133
2314-6141
出版者DOI
PubMedID
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Copyright © 2014 Suguru Shigemori et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
関連情報URL
部局名
生物圏科学研究科