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ID 39967
本文ファイル
著者
Yamaguchi, Nobuo
Romaidi
Isago, Yoshiaki
Tanahashi, Hisashi
キーワード
Vanadium
Ascidian
Metal-binding proteins
Membrane transporters
Reductase
NDC
生物科学・一般生物学
抄録(英)
Several families of ascidians accumulate extremely high levels of vanadium in their blood cells. The concentration of vanadium has been determined in each species; the highest concentration, found in Ascidia gemmata, reaches 350 mM, corresponding to 107 times that of sea water. How and why ascidians accumulate vanadium in a highly selective manner and at such extremely high levels have yet to be determined. To address these questions, our research group sought to identify the genes and proteins responsible for the accumulation and reduction of vanadium in vanadocytes, a type of blood cell, as well as the process of vanadium transport from sea water to blood cells through the branchial sac, intestine, and blood plasma. Here, we review the accumulation steps as a system, especially those related to the concentration and chemical species of vanadium at each step. A comprehensive analysis on each organ has already revealed several categories of protein families, such as vanadium-binding proteins and vanadium transporters. Herein, we also discuss the mechanisms by which ascidians selectively accumulate vanadium ions from a biochemical viewpoint.
掲載誌名
Coordination Chemistry Reviews
301–302巻
開始ページ
300
終了ページ
308
出版年月日
2015-10-14
出版者
Elsevier B.V.
ISSN
0010-8545
NCID
出版者DOI
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
author
権利情報
Copyright (c) 2014 Elsevier B.V. All rights reserved.
This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
関連情報URL(IsVersionOf)
http://doi.org/10.1016/j.ccr.2014.09.007
部局名
理学研究科