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ID 44621
本文ファイル
著者
Shimomura, Manabu
Kochi, Masatoshi
Hinoi, Takao 病院(医)
Adachi, Tomohiro
Kobayashi, Tsuyoshi
Tashiro, Hirotaka 大学院医歯薬保健学研究院(医)
Ohdan, Hideki 大学院医歯薬保健学研究科(医) 広大研究者総覧
キーワード
Venous thromboembolism
Pharmacologic prophylaxis
Lower abdominal surgery
NDC
医学
抄録(英)
Pharmacological prophylaxis was not routinely administrated following gastroenterological surgery because of concerns about bleeding complications. We tried to establish the original risk classification to determine the indication for pharmacological prophylaxis for selected patients at high risk of venous thromboembolism (VTE). One hundred and fifty-six consecutive patients who underwent lower abdominal elective surgery were divided into three groups (highest, high, and low risk groups) based on the original risk classification. Pharmacological prophylaxis was indicated for patients in the highest and high risk groups. We investigated safety and efficacy of the pharmacological prophylaxis based on this classification. Sixteen patients were classified in the highest, 50 in the high, and 90 in the low risk groups. Pharmacological prophylaxis was used for 59 cases (37.8%). There was no symptomatic pulmonary embolism or major bleeding complications. There were no significant differences in the occurrence of postoperative complications, analgesia use, and median postoperative pain scores for the three groups. In the highest and high risk groups administrated pharmacological prophylaxis, fibrin degradation products (FDP) and D-dimer did not change between postoperative day 1 and day 7. These data suggested the clinical significance of the pharmacological prophylaxis based on the original risk classification.
掲載誌名
Hiroshima Journal of Medical Sciences
65巻
3-4号
開始ページ
53
終了ページ
59
出版年月日
2016-12
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Copyright (c) 2016 Hiroshima University Medical Press
部局名
医歯薬保健学研究科
病院
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