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ID 33095
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別タイトル
Behavioral study of time perception with nigrostriatal lesion in rats. <Articles>
著者
氏田 麻美
キーワード
interval timing
peak procedure
6-OHDA
rat
NDC
心理学
抄録(英)
We studied the effects of an injection of 6-hydroxydopamine (6-OHDA) into the substantianigra of rats on the performance of timing behavior by using a peak interval (PI) procedure. Rats were trained on a PI 30-s procedure for 30 sessions. Then, subjects were divided into three groups: lesion (n=6), operational sham lesion (n=3) and intact (n=3). After 6-OHDA treatment, subjects were retrained on the PI 30-s procedure for 15 sessions and were checked for their timing behavior. Results indicated that sham and intact groups did not change the performance of timing between pre- and post- operation treatment. In the lesion group, a behavioral change occurred shortly after lesion treatment. They showed a dull curved peak in PI 30-s and peak time showed an in accuracy of 30-s. However, the lesion group recovered their performance following repeated training for 15 sessions. It is suggested that we should further investigate the durability of the 6-OHDA, as well as conduct histological analysis of the striatum, which is the dopamine (DA) projection ahead of the substantianigra. Such investigations would enable the identification of possible relationships between the function of substantianigra and time perception.
掲載誌名
広島大学大学院総合科学研究科紀要. I, 人間科学研究
6巻
開始ページ
1
終了ページ
11
出版年月日
2011-12-31
出版者
広島大学大学院総合科学研究科
ISSN
1881-7688
NCID
SelfDOI
言語
日本語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Copyright (c) 2011 by Graduate School of Integrated Arts and Sciences, Hiroshima University All rights reserved
部局名
総合科学研究科
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