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ID 37682
本文ファイル
著者
Orihashi, Kazumasa
Ishii, Osamu
Matsuura, Yuichiro
キーワード
Chronic atrial fibrillation
Electrophysiology
Fast Fourier transform analysis
Surgical ablation
NDC
医学
抄録(英)
Several authors have suggested that periodic activation is related to maintenance of atrial fibrillation (AF). The aim of this study was to examine periodic electrical activations in both atria that may lead to the generation and maintenance of AF associated with valvular diseases by means of fast Fourier transform (FFT) analysis. Atrial electrograms (AEGs) were analyzed in 15 persistent AF patients, who underwent pulmonary vein orifice (PVO) isolation with mitral valve surgery. Intraoperatively, AEGs of 4 seconds duration were acquired at 48 epicardial sites, 24 each from the right and left atrium (RA, LA). Dominant peaks (DPs) examined using FFT were present in 26% of all sampling points (380/1440). Prominent clustering of DPs was mostly observed on the LA. The mean AF cycle length (mAFCL) estimated from DP frequency was significantly shorter in LA than that in RA (178 ± 32 msec vs 24 7 ± 58, p = 0.0003). The shortest AF cycle length in each patient was mainly found in the LA. The PVO isolation procedures successfully eliminated AF in 87% of patients (13/15). In cases of recurred AF (2/15), the difference in mAFCL between bilateral atria was significantly smaller than in the case of successful AF elimination (17 ± 7 msec vs 76 ± 56, p = 0.042). FFT analysis of intraoperative mapping data clarified that periodic activity was present predominantly in LA. It may be possible to predict the efficacy of surgical procedures for eliminating AF using this technique.
内容記述
This work was supported in part by a Grant-inAid for Scientific Research from the Ministry of Education, Science, Sports, and Culture of Japan (no. 10470275; to Dr Sueda).
The main concepts of this work were presented at the 49th international congress of the European Society for Cardiovascular Surgery, Dresden, Germany, 2000.
掲載誌名
Hiroshima Journal of Medical Sciences
50巻
1号
開始ページ
27
終了ページ
35
出版年月日
2001-03
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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