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ID 27715
本文ファイル
著者
Urabe, Yuji
Hiyama, Tooru
NDC
医学
抄録(英)
Background and study aims: Endoscopic mucosal resection (EMR) has been applied to the treatment of superficial esophageal squamous cell carcinoma (SCC). The incidence and characteristics of metachronous multiple esophageal SCCs and Lugol-voiding lesions (LVLs) were investigated in a retrospective study in patients who had undergone EMR for superficial esophageal SCC. Patients and methods: 96 patients with esophageal SCC who had been treated by EMIR were followed up by endoscopy for 12 months or longer. Clinicopathologic parameters such as tumor size and location and presence of LVLs were examined. Results: 10 patients (10%) had synchronous multiple SCCs, and 12 (13%) developed metachronous multiple SCCs. The mean annual incidence of newly diagnosed tumor was 4.4%. The incidence of a speckled pattern of LVLs was 20/74 (27%) in patients with solitary SCC, 5/10 (50%) in synchronous multiple SCC, and 10/12 (83%) in metachronous multiple SCC. The incidence of the presence of speckled pattern of LVLs was significantly higher in patients with multiple SCCs than in those with solitary SCC (68% vs. 27%, P = 0.0004). Conclusions: Patients who have undergone EMR for esophageal SCC, especially those with metachronous multiple LVLs in the background mucosa, should undergo follow-up with close endoscopic observation using Lugol staining.
掲載誌名
Endoscopy
41巻
4号
開始ページ
304
終了ページ
309
出版年月日
2009
出版者
Georg Thieme Verlag KG
ISSN
0013-726X
NCID
出版者DOI
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
author
権利情報
(c) Georg Thieme Verlag Stuttgart
The original publication is available at www.thieme-connect.com
関連情報URL
部局名
医歯薬学総合研究科
保健管理センター