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ID 44825
本文ファイル
著者
Ohba, Hideo
Yamaguchi, Satoshi 病院(医)
Magaki, Takuro
Kolakshyapati, Manish
Sadatomo, Takashi
Kurisu, Kaoru 大学院医歯薬保健学研究科(医) 広大研究者総覧
キーワード
Hemangioblastoma
Leptomeningeal dissemination
von Hippel-Lindau disease
NDC
医学
抄録(英)
Hemangioblastoma disseminated along leptomeninges from the solitary cranial lesion without von Hippel-Lindau (VHL) disease is a quite rare instance with 23 cases reported in 40 years. We add a new case and discuss these rare instances. A 55-year-old female underwent surgery for total removal of cerebellar hemangioblastoma. Twenty months later, magnetic resonance (MR) images of the spinal cord revealed a tumor compressing the thoracic cord at T3-4 level which was removed en bloc by emergent spinal surgery. However, paraplegia and bowel bladder dysfunction recurred 5 months after the spinal surgery. Spine MR images showed diffuse enhancement of subarachnoid space. Exploratory surgery disclosed that the enhanced lesion was disseminated hemangioblastoma. After whole spinal irradiation, she was transferred to a palliative care hospital. Even after complete removal, possibility of leptomeningeal dissemination demands continuous follow-up. The mechanism of seeding of hemangioblastoma remains unclear, but attention must be paid to avoid spreading tumor cells during surgery because all the disseminated cases had precedent cranial surgery.
掲載誌名
Hiroshima Journal of Medical Sciences
66巻
1号
開始ページ
7
終了ページ
10
出版年月日
2017-03
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Copyright (c) 2017 Hiroshima University Medical Press
部局名
医歯薬保健学研究科
病院
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