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ID 30807
本文ファイル
著者
Shindo, Hajime
Mihara, Shoji
Kameyoshi, Yoshikazu
キーワード
Delayed pressure urticaria
Chronic urticaria
Pressure challenge test
Eosinophil
Steroid
NDC
医学
抄録(英)
Delayed pressure urticaria (DPU) is characterized by deep dermal wheals that appear in response to a local continuous pressure. Although it has been reported to complicate as many as 40% of cases of Caucasian patients with chronic urticaria, no definitive cases of Asian/Japanese patients have been reported in English literature. Here, we identified 17 cases of DPU, among 540 Japanese patients with urticaria (3.1%), based on careful history taking, pressure challenge test and, ideally, skin biopsy. Twelve out of 17 patients (70.5%) who undertook pressure challenge test developed wheal and erythema in the area of pressure 1-12 h later. Six out of 15 patients (40%) were positive for the autologous serum skin test. All cases were complicated with ordinary chronic urticaria, and all specimens of skin biopsies performed for 12 patients showed substantial eosinophil infiltration. All cases were resistant to antihistamines with or without other non-steroidal medications and eventually treated with 0.25-1.5 mg/day of betamethasone. However, 12 of them (70.6%) were able to cease steroid use because of cure or remission. For those cured or in remission, the duration of steroid administration and that from the onset to diagnosis was 11.2 +/- A 11.0 and 54.8 +/- A 60.2 months (mean +/- A SD), respectively. DPU may be identified as a relatively rare complication of Japanese patients with chronic idiopathic urticaria. A proper diagnosis and a small amount of steroid may be beneficial for the treatment of DPU.
掲載誌名
Archives of Dermatological Research
302巻
8号
開始ページ
613
終了ページ
617
出版年月日
2010-10
出版者
Springer
ISSN
1432-069X
NCID
出版者DOI
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
author
権利情報
Copyright (c) 2010 Springer
関連情報
The original publication is available at www.springerlink.com
関連情報URL
部局名
医歯薬学総合研究科