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ID 44646
本文ファイル
著者
Ishibashi, Takuya 病院(医)
Hirakawa, Katsuhiro 医療政策室
Takeno, Sachio 大学院医歯薬保健学研究科(医) 広大研究者総覧
キーワード
Pemphigus Vulgaris
Stenosis of esophageal orifice
Osteoporosis drug
NDC
医学
抄録(英)
Pemphigus vulgaris produces multiple and intractable erosions of the oral mucosa in the head and neck region. We describe a case of pemphigus vulgaris that showed erosions in the hypopharynx and stenosis of the esophageal orifice from an osteoporosis drug. A 73-year-old woman was admitted with oral intake difficulty and erosions in the hypopharynx. During the first admission, we could not make a definite diagnosis by biopsy or blood examination. The condition of the mucosa worsened subsequently; an esophagram showed marked stenosis of the esophageal orifice. As a possible factor exacerbating the stenosis, an osteoporosis drug was considered. The stenosis was improved by balloon expansion. One year after the first medical examination, we finally made a definite diagnosis of pemphigus vulgaris from the results of a blood examination in which anti-desmoglein 3 turned positive when the hypopharyngeal erosions and stenosis of the esophageal orifice became worse. Systemic treatment with a steroid was effective for the control of pemphigus vulgaris; restenosis of the esophageal orifice was recognized twice during a state of remission, and careful follow-up will be necessary in the future.
掲載誌名
Hiroshima Journal of Medical Sciences
66巻
2号
開始ページ
27
終了ページ
30
出版年月日
2017-08
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Copyright (c) 2017 Hiroshima University Medical Press
部局名
医歯薬保健学研究科
病院
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