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ID 39059
本文ファイル
著者
Nakanuno, Ryuichi
Yoshikawa, Hiroshi
キーワード
Inflammatory response
Propofol
Sevoflurane
Midazolam
NDC
医学
抄録(英)
Responses to surgical stress can be modulated by anesthetics. We prospectively compared the effects of two different anesthetic/sedative techniques on the peak postoperative bladder temperature (BT) and the postoperative C-reactive protein (CRP) level. Twenty patients who were scheduled to undergo elective thoracoabdominal esophagectomy were allocated to receive either propofol anesthesia followed by propofol sedation (PP group, n = 10) or sevoflurane anesthesia followed by midazolam sedation (SM group, n = 10). In each case, the patient’s peak bladder temperature was measured on the morning after surgery, and their serum CRP levels were assessed on postoperative days (POD) 1, 2, and 3. The patients’ postoperative clinical courses were also evaluated. The peak postoperative BT (°C) (37.6 ± 0.4 vs. 38.2 ± 0.6, respectively; p <0.05) and the CRP level on POD 2 (mg/dl) (14.3 ± 3.9 vs. 20.6 ± 3.9, respectively; p <0.05) were lower in the PP group than in the SM group. The peak postoperative BT was positively correlated with the CRP level on POD 2 (R = 0.533, p < 0.05). There were no significant differences between the clinical course-related parameters in both groups. Proposal anesthesia and postoperative propofol sedation resulted in a reduced peak postoperative BT and lower CRP levels on POD 2 after esophagectomy than sevoflurane anesthesia followed by midazolam sedation.
内容記述
This study was supported by the Hiroshima University Support Foundation.
掲載誌名
Hiroshima Journal of Medical Sciences
64巻
3号
開始ページ
31
終了ページ
37
出版年月日
2015-09
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Hiroshima University Medical Press
部局名
病院
医歯薬保健学研究科
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