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ID 45401
本文ファイル
著者
Nomura, Toshihito
Yoshimoto, Reiko
Kawabata, Ryoko
Matsubara, Toshiki
Narai, Seika
Oda, Kosuke
Fukushi, Masaya 大学院医歯薬保健学研究科(医) 広大研究者総覧
Irie, Takashi 大学院医歯薬保健学研究科(医) 広大研究者総覧
Sakaguchi, Takemasa 大学院医歯薬保健学研究科(医) 広大研究者総覧
キーワード
anti-viral reagents
cytotoxicity
influenza virus
feline calicivirus
NDC
医学
抄録(英)
Manda Koso is a commercial fermented plant product (FPP) made from 53 types of fruits and vegetables that are fermented for more than 3 years. We hypothesized that the FPP can prevent infection by influenza virus and human norovirus. Therefore, we investigated the effects of the FPP on influenza virus and feline calicivirus, a surrogate of human norovirus. We found that 10% FPP inactivated the influenza virus but not the feline calicivirus. Inhibition of the influenza virus was highly concentration-dependent: 1% and 0.3% FPP showed reduced inactivation efficacy. The effects of the FPP on the influenza virus-infected cells were investigated by addition of the FPP to the culture medium after virus infection. No suppressive effect of the FPP on influenza replication in MDCK cells was observed. The results showed that the FPP could inactivate influenza virus by affecting the virus particles.
掲載誌名
Hiroshima Journal of Medical Sciences
66巻
4号
開始ページ
97
終了ページ
101
出版年月日
2017-12
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Copyright (c) 2017 Hiroshima University Medical Press
部局名
医歯薬保健学研究科
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