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ID 34093
本文ファイル
著者
Yamamoto, Hideya 大学院医歯薬保健学研究院(医)
Ohashi, Norihiko
Ishibashi, Ken
Kunita, Eiji
Oka, Toshiharu
Horiguchi, Jun
Kihara, Yasuki 大学院医歯薬保健学研究院(医)
キーワード
Cardiovascular disease mortality
Coronary angiography
Coronary calcification
NDC
医学
抄録(英)
Background: Although the coronary artery calcium (CAC) score as measured with computed tomography (CT) is associated with cardiovascular mortality and morbidity in Western countries, little is known in Asian populations.

Methods and Results: Three hundred and seventeen Japanese patients (205 men and 112 women) were followed in the study and they underwent both coronary angiography and CT for CAC measurements. The frequencies of angiographic coronary artery disease (CAD) were 5%, 36%, 76%, 80%, and 94% (P<0.001) and the needs for revascularization were 5%, 26%, 53%, 59%, and 69% (P<0.001) in patients with CAC scores of 0 (n=64), 1-100 (n=58), 101-400 (n=76), 401-1,000 (n=70), and >1,000 (n=49), respectively. In the average of 6.0 (range, 1-10) years follow-up period, 34 patients died including 13 from reasons of cardiac disease. In a Cox proportional hazard model after adjustment for age and sex, traditional coronary risk factors, previous myocardial infarction, and the need for revascularization, the hazard ratio for cardiac mortality in patients with a CAC score >1,000 was 2.98 (95% confidence interval: 1.15-9.40) compared with those with a CAC score=0-100.

Conclusions: The CAC score has a predictive value for angiographical CAD and long-term mortality from cardiac disease in Japanese high-risk patients who undergo coronary angiography. (Circ J 2011; 75: 2424-2431)
掲載誌名
Circulation Journal
75巻
10号
開始ページ
2424
終了ページ
2431
出版年月日
2011
出版者
一般社団法人日本循環器学会
ISSN
1346-9843
NCID
出版者DOI
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Copyright (c) 2011 The Japanese Circulation Society.
関連情報URL
部局名
医歯薬学総合研究科