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ID 38381
file
title alternative
肺動脈発育不全に関する発生遺伝学的研究
creator
Satow, Yukio
Okamoto, Naomasa
Yi, Lee Juing
Sumida, Hiroshi
subject
DHS mice
Pdn mice
Polydactyly
Pulmonary hypoplasia
Polygene
NDC
Medical sciences
abstract
We have carried out the study on the heart anomalies of the DHS mice and Pdn mice fetuses and newborns which are known to produce genetically induced polydactyly. The results have revealed that the heart anomalies are mainly isolated hypoplasia of the pulmonary artery and that these anomalies are not always associated with polydactyly. The isolated hypoplasia of the pulmonary artery show a tendency to develop among uterine sibilings. These might suggest that the genetic traits of heart anomalies are controlled by the polygenic or multifactorial inheritances.
description
This study has been supported in part by Research Grants from Japanese Ministry of Education on the Experimental study of the morphogenesis of cardiovascular anomaly (448140), and on the Fine structure and pathogenesis of the heart and vessel (511102, Research Director: Professor Naomasa OKAMOTO).
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 31
issue
Issue 2
start page
97
end page
102
date of issued
1982-06-10
publisher
Hiroshima University School of Medicine
issn
0018-2052
ncid
pubmed id
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Research Institute for Radiation Biology and Medicine
Graduate School of Biomedical Science
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