このエントリーをはてなブックマークに追加
ID 35018
file
creator
Torikoshi-Hatano, Aiko
Shiraishi, Hiroaki
Arima, Yousuke
Toubou, Hirokazu
Ezaki, Jiro
Morikawa, Masami
subject
Aspartic acid
Racemization
Skull bone
NDC
Medical sciences
abstract
In forensic medicine, the personal identification of cadavers is one of the most important tasks. One method of estimating age at death relies on the high correlation between racemization rates in teeth and actual age, and this method has been applied successfully in forensic odontology for several years. In this study, we attempt to facilitate the analysis of racemized amino acids and examine the determination of age at death on the basis of the extent of aspartic acid (Asp) racemization in skull bones.  

The specimens were obtained from 61 human skull bones (19 females and 42 males) that underwent judicial autopsy from October 2010 to May 2012. The amount of D-Asp and L-Asp, total protein, osteocalcin, and collagen I in the skull bones was measured. Logistic regression analysis was performed for age, sex, and each measured protein.  

The amount of D-Asp in the female skull bones was significantly different from that in the male skull bones (p = 0.021), whereas the amount of L-Asp was similar. Thus, our study indicates that the amount of D-Asp in skull bones is different between the sexes.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 61
issue
Issue 4
start page
91
end page
100
date of issued
2012-12
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
rights
(c) Hiroshima University Medical Press.
department
Graduate School of Biomedical & Health Sciences
Graduate School of Biomedical Science
他の一覧