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ID 20763
file
creator
Shimose, Shoji
Sugita, Takashi
Nobuto, Hiroo
Tanaka, Kumi
subject
Schwannoma
Major nerve
Intramuscular
Target sign
MRI
Tinel-like sign
NDC
Medical sciences
abstract
Background: A schwannoma is a benign peripheral nerve tumor. Predicting the involvement of a nerve on symptoms or MR findings is crucial to the diagnostic process. Purpose: To compare symptoms, MR findings, and histological findings between major nerve schwannomas and intramuscular schwannomas. Material and Methods: Thirty-four patients with 36 schwannomas (29 major nerve schwannomas and 7 intramuscular schwannomas) surgically excised and proven histologically were retrospectively reviewed. Results: Frequencies of the Tinel - like sign, split-fat sign, entering and exiting nerve, and low-signal margin indicate the presence of the nerve and were significantly higher in major nerve schwannomas than in intramuscular schwannomas. In tumor morphological patterns (the target sign, inhomogeneous pattern, and homogeneous pattern), there were no significant differences between major nerve schwannomas and intramuscular schwannomas. Schwannomas showing the target sign histologically tended to be less degenerative. All major nerve schwannomas and 5 intramuscular schwannomas produce some characteristic symptoms and/or MR findings, but two intramuscular schwannomas didn't have any characteristic symptoms and findings. Conclusion: In major nerve schwannomas, the Tinel - like sign, split-fat sign, entering and exiting nerve, and low-signal margin are commonly observed and useful for diagnosis. In intramuscular schwannomas, these characteristic findings are less common, which makes diagnosis difficult.
journal title
Acta Radiologica
volume
Volume 48
issue
Issue 6
start page
672
end page
677
date of issued
2007
publisher
Informa Healthcare
issn
0284-1851
ncid
publisher doi
pubmed id
language
eng
nii type
Journal Article
HU type
Journal Articles
DCMI type
text
format
application/pdf
text version
author
rights
Copyright (c) 2007 Taylor & Francis.
This is an electronic version of an article published in "Acta Radiologica, Volume 48, Issue 6 (2007) pages 672 - 677" Natural Product Research is available at: http://dx.doi.org/10.1080/02841850701326925
relation url
department
Graduate School of Biomedical Science